Involvement of ROS in Curcumin-induced Autophagic Cell Death
نویسندگان
چکیده
منابع مشابه
Involvement of ROS in Curcumin-induced Autophagic Cell Death.
Many anticancer agents as well as ionizing radiation have been shown to induce autophagy which is originally described as a protein recycling process and recently reported to play a crucial role in various disorders. In HCT116 human colon cancer cells, we found that curcumin, a polyphenolic phytochemical extracted from the plant Curcuma longa, markedly induced the conversion of microtubule-asso...
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Curcumin (1), a natural polyphenolic compound, has shown strong antioxidant and anticancer activities. Several molecular mechanisms have been attributed to its inhibitory effects on a wide range of tumor cells. In this study, the response of the chronic myeloid leukemia cell line K562 cells to 1 is investigated. Curcumin inhibited the viability of K562 cells in a dose- and time-dependent manner...
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This corrects the article DOI: 10.1038/cddis.2017.100.
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Oleanolic acid (OA) has a wide variety of bioactivities such as hepatoprotective, anti-inflammatory and anti-cancer activity and is used for medicinal purposes in many Asian countries. In the present study, the effect of OA on induction of autophagy in human hepatocellular carcinoma HepG2 and SMC7721 cells and the related mechanisms were investigated. MTT assay showed that OA significantly inhi...
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ژورنال
عنوان ژورنال: The Korean Journal of Physiology and Pharmacology
سال: 2011
ISSN: 1226-4512
DOI: 10.4196/kjpp.2011.15.1.1